Larotinib (Vitrakvi / Larotrectinib) is the first oral tyrosine kinase inhibitor approved for the treatment of NTRK gene fusion solid tumors. It is suitable for all types of solid tumors, regardless of their original location. NTRK gene fusion is a kind of chromosomal abnormality, which is formed when NTRK gene combines with another unrelated gene, and then translates and produces abnormal TRK protein.
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